Organaization

Understanding chromosome condensation during mitotic phase through the mode coupling between bend and twist

In geometry, the “kink” in chromatin or DNA is described by the basic modes: twist and supercoil. For example, when we bend the polymer chain including twist which is a kink around the centerline, the supercoiled chain appears. In this research, by using the coarse-grained molecular dynamics simulation, we discuss the effect of the “kink” on the shape and the dynamics of chromosome condensation.


  • Hiroshi Yokota

    Hiroshi Yokota Project Leader

    RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS)
    https://ithems.riken.jp/ja
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