Organization

Phase separation model with multiple degrees of freedom and its application to large scale genome organization

In this research project, we investigate the phase separation behavior of chromatin polymers, where the focus is on the multiple degrees of freedom present in the system. We first develop a basic statistical physics approach to analyze the multi-component liquid-liquid phase separation, and make use of the framework to understand the formation of meso-scale chromatin organization in nucleus.
 


Back to Research Projects (FY2023-2024)